Inflammatory bowel disease (research project)
There are 2,6/100 000 children affected by inflammatory bowel disease before 6 years old. Etiologic studies do not show any…
Rare retinopathies (research program)
The embryonic eye is nourished and oxygenated by transient fetal vessels called hyaloids, which regress after birth to be replaced…
Brain cancer
BACKGROUND: Transforming growth factor (TGF)-β triggers metastasis through epithelial-mesenchymal transition (EMT) to which a role for a membrane type-1 matrix…
Zebrafish and the study of rare developmental diseases (research program)
Crédit: Pr Éric Samarut
Hirschsprung desease
Immunofluorescent staining of colon of Holstein; Nestin-CreERT2; R26R-YFP mice at P20. The mice were treated with tamoxifen (2mg/ml; 50 μl)…
Batten disease
Mutations in the CLN5 and CLN3 genes cause a deadly lysosomal storage disorder called neuronal ceroid lipofuscinosis (NCL), more commonly…